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RASĀYAN - Journal Of Chemistry Vol.1, No.3, 429-692 (2008)

REVERSE PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHIC DETERMINATION OF ORLISTAT PELLETS 50.0%

Authors: M.V. Basavasewara Rao*, B.C.K Reddy, T.Srinivas Rao, P. Muralidhar

Department of Chemistry, G.I.T.A.M. University, Visakhapatnam-530045, A.P., India;Email: vbrmandava@yahoo.com

A Simple and precise reverse phase high performance liquid chromatographic method has been developed for the determination of Orlistat  pellets 50.0%. A Inertsil ODS  3V(5microns,25 x 4.6mm) column, in isocratic mode, with Methanol, Acetonitrile and trifluroaceticacid (82.5:17.5:0.01)as mobile phase. The flow rate is 1ml/minute and effluent is monitored at 210nm.

Keywords : Orlistat pellets, liquid chromatographic method, Inertsil ODS 3V.

Page No. : 636-638 (Received:16 August2008 Accepted: 23 August 2008 RJC-231)