CONTRACEPTIVE PROPERTY OF NITROGEN / OXYGEN SULFUR DONOR HETEROCYCLIC COMPOUNDS

Authors: Ashu Chaudharya , N. Sharmab, P. Sharmab , N.D. Jasujab, G. Sharmac, S. C. Joshib and R.V. Singhd

aDepartment of Chemistry, Banasthali University, Rajasthan-304022, India;bDepartment of Zoology, University of Rajasthan, Jaipur-302 004, India;cDepartment of Bioscience, Suresh Gyan Vihar University, Jaipur;dDepartment of Chemistry, University of Rajasthan, Jaipur-302 004, India;E.mail : ashuchaudhary21@gmail.com

Fertility regulation is certainly an essential pathway but not sufficient in itself to the optimization of population rise. A large variety of substances both natural and synthetic have been shown to intercept pregnancy either during the pre-implantation or post-implantation stages of pregnancy            The development of hormonal contraceptives is one of the greatest scientific achievements of the 20^th Century. About three decades back, some important discoveries were made which opened a new era in the control of conception and fertility, viz: the discovery of the steroidal drugs, including steroidal contraceptives like estradiol and progesterone. This review concern the development on contraceptive property of the Non-Steroidal  compounds. The Non-Steroidal  compounds with a variety of nitrogen/ oxygen & sulfur donor containing heterocycles developed mainly during last decade is reviewed.

Keywords : Hormonal Contraceptives, Chemical Contraception, Non- steroidal and Heterocyclic compounds