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RASĀYAN - Journal Of Chemistry Vol.2, No.1, 1-256 (2009)

ALUM CATALYZED EFFICIENT ONE POT SYNTHESIS OF α-AMINO NITRILES

Authors: Suresh and Jagir S. Sandhu*

Department of Chemistry, Punjabi University, Patiala-147 002, Punjab, India;E-mail: j_sandhu2002@yahoo.com

α-Amino nitriles are prepared in a one pot three component coupling of aldehydes, amines and trimethylsilyl cyanide employing catalytic amount of Alum at room temperature.

Keywords : Alum, α-Amino nitriles, aldehydes, amines, trimethylsilyl cyanide.

Page No. : 182-185 Received: 21 February 2009 Accepted: 1 March 2009 RJC-335