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RASĀYAN - Journal Of Chemistry Vol.2, No.4, 769-1011(2009)

SYNTHESIS OF 5-UNSUBSTITUTED -3,4-DIHYDROPYRIDINE-2-(1H)- ONES USING NBS AS A CATALYST UNDER SOLVENT FREE CONDITIONS

Authors: Shivaji Pandit*1, Ruksana Shaikh2 and Vikram Pandit3

1Department of Chemistry, Arts, Science and Commerce College Kolhar, Tal. Rahata, Dist. Ahmednagar 413710 (MS) India;2P. G. and Research Centre, Department of Chemistry, P. V. P. College Pravaranagar (Loni. kd) Tal. Rahata. Dist. Ahmednagar. 413713. (MS). India; 3P. G. and Research Centre, Department of Chemistry, Fergusson College Pune, (MS) India.Email: akankshapandit2002@yahoo.com

The development of efficient and versatile catalytic system for one pot multicomponent reaction is an active ongoing research area for further improvement towards milder reaction conditions, N-bromosuccinimide (NBS) has been used an efficient catalyst for the synthesis of 5-unsubstituted-3,4-dihydropyrimidin-2-(1H)-ones at room temperature under solvent free conditions.

Keywords : Dihydropyrimidine derivatives, Enolizable ketones, Aldehydes, Multicomponent, N-Bromosuccinimide, Solvent-free

Page No. : 907-911 (Received: 30 October 2009 Accepted: 13 November 2009 RJC-478)