SYNTHESIS, CHARACTERIZATION AND CHELATING PROPERTIES OF INDOLE-SALICYLIC ACID COMBINED MOLECULE

Authors: Piyush Vyas1, Prakash Patel1 and Bhargav Trivedi2

1Sheth M N Science College, Patan, Gujarat, India; 2J & J College of Science, Nadiad, Gujarat, India; E-mail: uppatel2000@yahoo.com

The treatment of 2-Chloro-1-indol-1-yl-ethanone with 4-aminosalicylic acid afford a 2-Hydroxy-4-(2-indol-1-yl-2-oxo-ethylamino)-benzoic acid (HIBA) .The transition metal complexes of Cu²⁺, Co²⁺ ,Ni²⁺, Mn²⁺, Zn²⁺ and Fe³⁺ of HIBA have been prepared and characterized by elemental analyses, spectral studies, magnetic moment determination, molar conductivity measurement and microbicidal activity.

Keywords : 2-Chloro-1-indol-1-yl-ethanone, 4-aminosalicylic acid, metal chelates, spectral studies, magnetic moment, antibacterial and antifungal activity