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RASĀYAN - Journal Of Chemistry Vol.4(1), 1-222, 2011

SYNTHESIS AND BIOLOGICAL ACTIVITY OF SOME 2-AMINO-4,6-SUBSTITUTED-DIARYLPYRIMIDINES: REACTION OF SUBSTITUTED CHALCONES WITH GUANIDINIUM CARBONATE

Authors: Vandana Sharma* and K. V. Sharma

*E-mail: vandanak_sharma@yahoo.co.in

A series of substituted 2-Amino-4,6-diarylpyrimidines were synthesized by the reaction of appropriately substituted chalcones and guanidinium carbonate in DMF. The synthesized pyrimidines have been characterized on the basis of their chemical properties and spectroscopic data. These compounds were screened for biological activity against a variety of test organisms.

Keywords : Substituted Chalcones, Guanidinium Carbonate, pyrimidines, 2-Amino-4,6- diarylpyrimidines.

Page No. : 17-23 RJC-686